What Type Of Cholesterol Is Good

Add These Foods To Lower Ldl Cholesterol

Different foods lower cholesterol in various ways. Some deliver soluble fiber, which binds cholesterol and its precursors in the digestive system and drags them out of the body before they get into circulation. Some give you polyunsaturated fats, which directly lower LDL. And some contain plant sterols and stanols, which block the body from absorbing cholesterol.

1. Oats. An easy first step to lowering your cholesterol is having a bowl of oatmeal or cold oat-based cereal like Cheerios for breakfast. It gives you 1 to 2 grams of soluble fiber. Add a banana or some strawberries for another half-gram. Current nutrition guidelines recommend getting 20 to 35 grams of fiber a day, with at least 5 to 10 grams coming from soluble fiber.

2. Barley and other whole grains. Like oats and oat bran, barley and other whole grains can help lower the risk of heart disease, mainly via the soluble fiber they deliver.

3. Beans. Beans are especially rich in soluble fiber. They also take a while for the body to digest, meaning you feel full for longer after a meal. Thats one reason beans are a useful food for folks trying to lose weight. With so many choices from navy and kidney beans to lentils, garbanzos, black-eyed peas, and beyond and so many ways to prepare them, beans are a very versatile food.

4. Eggplant and okra. These two low-calorie vegetables are good sources of soluble fiber.

What Are Good And Bad Cholesterol

Rather than two different kinds of cholesterol that are good and bad, there are two different types of lipoproteins that cholesterol travels in. Having some of both types of lipoproteins is essential for good health.

High-density lipoproteins, called HDL cholesterol, are often thought of as good because they remove cholesterol from your arteries and take it back to your liver to process and eliminate.

Low-density lipoproteins, called LDL cholesterol, are thought of as the bad cholesterol, because they leave cholesterol in your arteries. While you need some LDL and HDL cholesterol for your body to work properly, too much cholesterol in total can lead to health problems, as the extra LDL cholesterol builds up in your arteries.

Healthy Eating Tips To Lower Cholesterol

As well as sticking to a varied and healthy diet, try these tips to help you manage your cholesterol:

• Limit takeaway foods to once a week .
• Limit salty, fatty and sugary snack foods to once a week .
• Eat plenty of vegetables aim for 5 serves of vegetables every day. .
• Choose wholegrain breads, cereal, pasta, rice and noodles.
• Snack on plain, unsalted nuts and fresh fruit .
• Include legumes such as chickpeas, lentils, split peas), beans into at least two meals a week. Check food labels and choose the lowest sodium products.
• Use spreads and margarines made from healthy unsaturated fats instead of those made with saturated fat .
• Use healthy oils for cooking some include canola, sunflower, soybean, olive , sesame and peanut oils.
• Use salad dressings and mayonnaise made from oils such as canola, sunflower, soybean, olive , sesame and peanut oils.
• Include 2 or 3 serves of plant-sterol-enriched foods every day .
• Have 2 to 3 portions of oily fish every week. Fish may be fresh, frozen or canned.
• Include up to 7 eggs every week.
• Select lean meat and limit unprocessed red meat to less than 350g per week.
• Choose reduced fat, no added sugar milk, yoghurt, or calcium-added non-dairy food and drinks.
• Limit or avoid processed meats including sausages and deli meats .

If you are having trouble with your cholesterol levels, a dietitian can help you to eat healthily for your specific needs.

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How Often Should I Get A Cholesterol Test

When and how often you should get a cholesterol test depends on your age, risk factors, and family history. The general recommendations are:

For people who are age 19 or younger::

• The first test should be between ages 9 to 11
• Children should have the test again every 5 years
• Some children may have this test starting at age 2 if there is a family history of high blood cholesterol, heart attack, or stroke

For people who are age 20 or older::

• Younger adults should have the test every 5 years
• Men ages 45 to 65 and women ages 55 to 65 should have it every 1 to 2 years

Regulation Of Cholesterol Synthesis

Biosynthesis of cholesterol is directly regulated by the cholesterol levels present, though the homeostatic mechanisms involved are only partly understood. A higher intake from food leads to a net decrease in endogenous production, whereas lower intake from food has the opposite effect. The main regulatory mechanism is the sensing of intracellular cholesterol in the endoplasmic reticulum by the proteinSREBP . In the presence of cholesterol, SREBP is bound to two other proteins: SCAP and INSIG-1. When cholesterol levels fall, INSIG-1 dissociates from the SREBP-SCAP complex, which allows the complex to migrate to the Golgi apparatus. Here SREBP is cleaved by S1P and S2P , two enzymes that are activated by SCAP when cholesterol levels are low.

Cholesterol synthesis can also be turned off when cholesterol levels are high. HMG-CoA reductase contains both a cytosolic domain and a membrane domain. The membrane domain senses signals for its degradation. Increasing concentrations of cholesterol cause a change in this domain’s oligomerization state, which makes it more susceptible to destruction by the proteasome. This enzyme’s activity can also be reduced by phosphorylation by an AMP-activated protein kinase. Because this kinase is activated by AMP, which is produced when ATP is hydrolyzed, it follows that cholesterol synthesis is halted when ATP levels are low.

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How Do You Prepare For A Cholesterol Test

In most cases, youll need to fast for nine to 12 hours before the test. Make sure you tell the person drawing your blood how long it has been since you ate or drank anything that wasnt water.

There are some cases when a cholesterol test is done without fasting. This is true for tests done at health screenings and may be true for people younger than 20 or for people who are unable to fast.

Some medical societies believe that fasting is not necessary to get a true picture of lipid levels in the blood, while other associations stand by the belief that fasting gives a better idea of a persons heart disease risk. You should be clear on whether or not you need to fast, and for how long, before you go for the blood test.

Plasma Transport And Regulation Of Absorption

As an isolated molecule, cholesterol is only minimally soluble in water, or hydrophilic. Because of this, it dissolves in blood at exceedingly small concentrations. To be transported effectively, cholesterol is instead packaged within lipoproteins, complex discoidal particles with exterior amphiphilic proteins and lipids, whose outward-facing surfaces are water-soluble and inward-facing surfaces are lipid-soluble. This allows it to travel through the blood via emulsification. Unbound cholesterol, being amphipathic, is transported in the monolayer surface of the lipoprotein particle along with phospholipids and proteins. Cholesterol esters bound to fatty acid, on the other hand, are transported within the fatty hydrophilic core of the lipoprotein, along with triglyceride.

There are several types of lipoproteins in the blood. In order of increasing density, they are chylomicrons, very-low-density lipoprotein , intermediate-density lipoprotein , low-density lipoprotein , and high-density lipoprotein . Lower protein/lipid ratios make for less dense lipoproteins. Cholesterol within different lipoproteins is identical, although some is carried as its native “free” alcohol form , while others as fatty acyl esters, known also as cholesterol esters, within the particles.

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How To Manage Cholesterol With Food

• Identify foods that are high in saturated fat. These are found primarily in processed foods like French fries, packaged bakery products, bacon, cold cuts, and aged cheeses. Choosing fresh and natural foods such as fruits and vegetables is a good option to reduce cholesterol consumption.
• Promoting the loss of body weight contributes to the reduction of cholesterol levels as well as cardiovascular diseases.
• Exercising regularly helps raise HDL cholesterol levels as well as contributing to increased muscle mass and decreased body weight.

Taking care of yourself also involves taking care of your cardiovascular health. Approach your team of health professionals and create a plan to take care of your physical and emotional health with their help.

When Is It Ordered

The calculation of non-HDL-C can be reported as an additional parameter to the traditional lipid profile, along with total cholesterol, HDL-C, LDL-C and triglycerides when a person has a routine health exam.

AdultsIt is recommended that all adults with no risk factors for heart disease be tested every four to six years.

For people who have one or more major risk factors for heart disease , a fasting lipid profile may be ordered more frequently.

Major risk factors for heart disease other than a high LDL-C include:

• Cigarette smoking

The concentration expressed in mg/dl or mmol/l.

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How Can I Lower My Cholesterol By Making Lifestyle Changes

You can lower your cholesterol levels by making lifestyle changes, and through taking medicines if that’s what your doctor advises. Some people will only need to improve their lifestyle and diet to get their cholesterol to a safe level. Others may need to take cholesterol-lowering medicines, as well.

What Treatments Are Available For High Cholesterol

Treatment may include:

• Addressing risk factors. Some risk factors that can be changed include lack of exercise and poor eating habits.

• Cholesterol-lowering medicines. Medicines are used to lower fats in the blood, particularly LDL cholesterol. Statins are a group of medicines that can do this. The two most effective types are atorvastatin and rosuvastatin. Other medicines that lower cholesterol levels are ezetimibe and PCSK9 inhibitors.

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How To Lower Your Cholesterol

Your doctor can measure your cholesterol levels using a blood test. A high cholesterol level means you might be at risk of heart disease and stroke. You wont necessarily have any symptoms of having high cholesterol, so you doctor might test it regularly to keep an eye on your levels.

A cholesterol test looks at the amount of both HDL and LDL cholesterol in your body. It will also show your triglyceride level, which is a type of fat in your bloodstream, as high triglyceride levels can also indicate a higher risk of heart disease.

If youve had a test showing you have high cholesterol levels, lifestyle changes might help you to lower your levels. Reduce your cholesterol by:

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How Is Cholesterol Measured

Most people with high cholesterol feel perfectly well and often have no symptoms. The best way to find out if your cholesterol is high is to have a blood test .

Visit your GP to determine whether you need to lower your cholesterol level and what action to take.

GPs can also do a heart health check, that calculates your heart disease and stroke risk.

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Preparing And Eating Eggs Safely

Now, there are important safety aspects to consider when it comes to egg preparation. Eggs can contain salmonella, and if not cooked properly, can cause illness. Under cooked eggs present a food poisoning risk. Make sure to cook your eggs until the yolk and white are firm. Scrambled eggs should not be runny.

Simple precautions can eliminate much of the potential salmonella risk. As with any other perishable food, make sure you wash your hands and all preparation surfaces. Dont eat eggs with cracked or broken shells. Also, steer clear of eggs that have been out of refrigeration for more than two hours. Dont store egg dishes for more than a few days in the fridge.

What Foods Help Lower Ldl Cholesterol

A heart-healthy diet that is high in fiber and plant-based foods can help lower total and LDL cholesterol levels. Mainly vegetarian or vegan diets have been shown to reduce cholesterol levels and the risk of blocked arteries. Foods that can help lower LDL cholesterol include:

Oatmeal

• and reduce stress by using stress reduction techniques like Yoga, Tai Chi, or meditation.

If diet, exercise, and lifestyle changes are not enough to lower your cholesterol to healthy ranges, then your doctor may prescribe medication. The type of cholesterol lowering medication depends upon your levels of LDL, HDL, and triglycerides and any current medications you are currently taking, and your overall health.

Medication options to reduce cholesterol include statins, niacin, and fibric acid agents . Your doctor may prescribe one or several types of these drugs to reduce your cholesterol levels to a healthy range.

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What Can Raise My Risk Of High Cholesterol

A variety of things can raise your risk for high cholesterol:

• Age. Your cholesterol levels tend to rise as you get older. Even though it is less common, younger people, including children and teens, can also have high cholesterol.
• Heredity. High blood cholesterol can run in families.
• Weight. Being overweight or having obesity raises your cholesterol level.
• Race. Certain races may have an increased risk of high cholesterol. For example, African Americans typically have higher HDL and LDL cholesterol levels than whites.

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Questions To Ask Your Doctor

If testing shows you have high cholesterol, you may want to ask your doctor these questions at your next visit.

1. What are the dangers of having high cholesterol? Can other problems develop?

2. What could have caused my cholesterol to be too high? Is it inherited?

3. Are there things I can do at home or in my life to reduce my cholesterol?

4. Is medicine necessary? Are there alternative treatments?

5. If medicine is needed, how does the medicine work?

6. How long can I take medicine? What are the side effects? Is long-term use harmful?

7. How can exercise help to lower my cholesterol?

8. Where can I learn more about how to live with high cholesterol?

9. What changes should I make to the way I eat?

10. How often do I need to get my cholesterol level checked?

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Pcsk9 As A Therapeutic Target For Dyslipidemia

The establishment of a link between PCSK9 and cholesterol metabolism was rapidly followed by the discovery that selected mutations in the PCSK9 gene caused autosomal dominant hypercholesterolemia , suggesting that the mutations confer a gain of function by increasing the normal activity of PCSK9. This was supported by an experiment in which wild-type and mutant PCSK9 were expressed at high levels in the livers of mice hepatic LDLR protein levels fell dramatically in mice receiving either the wild-type or the mutant PCSK9 . No associated reductions in LDLR mRNA levels were observed, indicating that overexpression of PCSK9, whether mutant or wild type, reduces LDLR through a posttranscriptional mechanism.

How Cholesterol Is Tested

Not sure what to expect when you get your cholesterol tested? Well, all it takes is a simple blood test. Health care professionals simply take a blood sample from a vein in your arm with a needle. You may be asked not to eat or drink for 9 to 12-hours prior to the blood test.

Once your results come in, the doctor will see whether youre at a healthy level. You may need to boost your HDL levels or perhaps lower your LDL levels. Whatever the results are, you can discuss with your doctor to find out how you can achieve optimal cholesterol levels.

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You Dont Need To Avoid Eggs And Seafood

Some foods are high in cholesterol but are fine to eat in moderation, as long as your overall diet is low in saturated fats. For example:

• Egg yolks a single egg yolk contains 200250 mg of cholesterol, which is almost the uppermost recommended daily intake . However, reducing egg intake is probably not important for healthy people with normal blood cholesterol levels.
• Seafood prawns and seafood contain some cholesterol, but they are low in saturated fat and also contain healthy omega-3 fatty acids. Seafood is a healthy food and should not be avoided just because it contains cholesterol. However, avoid fried and battered seafood.

Increase Your Physical Activity

Physical activity increases levels of HDL cholesterol the good cholesterol that removes LDL cholesterol from the blood. Vigorous aerobic exercise is best.

If you havent been exercising much lately, gradually build up to the recommended amount of physical activity:

• People aged 18-64 years should do 30 to 60 minutes of moderate-intensity physical activity on most days of the week.
• People aged 65 years and over should aim for a total of 30 minutes of moderate physical activity on most days .

Moderate-intensity exercise is a level that increases your heart rate and breathing but allows you to keep talking. Vigorous intensity exercise makes your heart rate higher and makes you breathe more heavily.

Resistance training and muscle-toning exercises can increase HDL cholesterol. Aim to do this twice a week.

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Keep Your Cholesterol Counts Under Control

Maintaining healthy levels of cholesterol is manageable. Medication is key, along with eating a healthy diet with lots of vegetables and getting regular exercise.

The experts at the USC CardioVascular Thoracic Institute can help you understand your count and give you the support you need to maintain cholesterol levels needed for a healthy heart. Request an appointment today or call .