I Was Athletic And Fit And Still Had High Cholesterol
When diet and exercise werent enough to control this executives numbers, medication helped him reclaim his health.
High cholesterol, or hyperlipidemia, runs in Dean Mastrojohns family. So when the Maywood, New Jersey, residents doctor encouraged him to make some lifestyle modifications to lower his risk, he took the guidance seriously.
My doctor the same one my parents have kept a watchful eye on me and strongly suggested I try to lose some weight and exercise as much as possible to avoid medication, says Mastrojohn, 47, a senior vice president at Goodfuse, a communications company in New York City. I lost nearly 20 pounds and was exercising regularly weight lifting, playing pickup basketball games, etc. and was very fit.
But after losing the recommended amount of weight to get his cholesterol in check, Mastrojohn received some surprising news: His LDL cholesterol and triglycerides had increased.
It was right then that told me my condition was clearly genetic and he strongly suggested I begin taking a statin, says Mastrojohn. Ill never forget it. I couldnt believe it.
What Kind Of Test Measures Cholesterol
Your provider checks your cholesterol levels through a blood test called a lipid panel . Your provider will draw blood from a vein in your arm and send the blood to a lab for analysis. Be sure to closely follow your providers instructions on how to prepare for the test. Youll likely need to fast for 12 hours beforehand. This means avoiding all foods and drinks except water.
When your results come in, your provider will let you know. You may also be able to access your results through your electronic medical record.
Your lipid panel gives you the following numbers:
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Microinjection Of Zebrafish Embryos
To compare antioxidant and anti-inflammatory activities of HDL between slim and plump, HDL3 from each group was injected into zebrafish embryos, as in our previous report . Embryos at 1-day post-fertilization were individually microinjected using a pneumatic picopump equipped with a magnetic manipulator and a pulled microcapillary pipette-using device . To minimize bias, injections were performed at the same position on each yolk. Filter-sterilized solution of each LDL or HDL3 was injected into flasks of embryos. Following injection, live embryos were observed under a stereomicroscope and photographed using a Motic cam2300 CCD camera.
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What Can Happen If You Have Atherosclerosis
If your arteries become clogged up with blood fats your blood can’t flow around your body as easily. This can lead to a number of diseases of the heart and blood vessels.
These are known together as cardiovascular disease or CVD cardio refers to the heart, and vascular refers to the blood vessels.
Coronary heart disease
This is where the arteries have become clogged up and stiff. The blood cant flow around the body and back to the heart easily, and blood clots can form. This can lead to chest pain, heart failure, heart attacks and strokes. This is the most common type of heart disease.
This is a dull, heavy or tight pain in the chest which can spread to the left arm, neck, jaw or back. It happens when the arteries leading to the heart have become narrowed and the heart can’t get enough blood. The pain is caused by a lack of oxygen. It can be brought on by exercise or activity, as the heart needs more oxygen during physical activity.
This is a medical emergency. It happens when an artery leading to the heart becomes completely blocked, often by a blood clot, cutting off the blood supply. Part of the heart muscle quickly dies, but if its treated quickly, the blockage can be removed.If you think you or someone you are with is having a heart attack, call 999 straight away. The signs of a heart attack include:
- a crushing pain in the chest
- suddenly feeling very anxious.
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Ferric Reducing Ability Of Plasma Assay And Paraoxonase Activity
The ferric reducing ability of plasma was determined using the method described by Benzie and Strain . The antioxidant activities of individual HDL fractions were estimated by measuring increases in absorbance produced by generated ferrous ions. Paraoxonase-1 activity was then determined by measuring the initial velocity of p-nitrophenol production at 37°C, as determined by measuring the absorbance at 405 nm , as described previously with slight modifications . Prior to the measurement, HDL was extensively dialyzed against PBS to remove EDTA.
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Skip The Cakes And Pastries
Baked goods may taste good, but they are loaded with sugar and saturated fat that can make triglyceride levels climb. Bake goods and pastries may also contain dangerous trans fats. These types of fats should be avoided in all amounts. Read nutrition labels before you indulge in baked goods. If you strive for weight loss, to reduce high cholesterol, and to modify other factors for cardiovascular disease, limit your consumption of baked goods. Eat high-fiber, whole grain foods instead of baked goods. Just be mindful to stay within the carbohydrate intake limit your doctor has established for you to reach your triglyceride goals.
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Can You Be Thin And Have High Cholesterol
One of the most common misconceptions about high cholesterol is that thin people dont have it. As mentioned, overweight individuals are more likely to have high cholesterol. However, not all of them have the condition.
The same goes for a skinny person with high cholesterol. Having a thin body does not mean a person is healthier than those who have bigger builds. Different people with different body types can develop high cholesterol, especially if theyre constantly living an unhealthy lifestyle.
High cholesterol in skinny people is usually unnoticeable, since their body does not physically show that they are consuming more saturated and trans fat than what their body needs. Most of the time, a skinny person with high cholesterol only becomes aware of their condition if they regularly check their cholesterol level.
So, can you be thin and have high cholesterol? Yes, no matter what diet and what exercise a person does, even if they are skinny or not, anyone can have high cholesterol.
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Misconception: Using Margarine Instead Of Butter Will Help Lower Cholesterol
Butter is high in saturated fat and has some trans fat raising LDL cholesterol and contributing to atherosclerosis. But many hard margarines also have a high amount of saturated and trans fat.
The healthiest choice is a liquid or soft tub margarine. These are made with vegetable oils. They have less partially hydrogenated fat and saturated fat than solid spreads such as hard stick margarine and butter. Look for margarines that say 0 g trans fat on the Nutrition Facts label.
Switching from butter to soft margarine is a good step. But by itself, it probably wont reduce your cholesterol to healthy levels.
Add More Fiber To Your Diet
Eating soluble fiberwhich dissolves in water to form a gel-like materialcan prevent cholesterol from entering your bloodstream. This can also aid weight loss efforts by making you feel full for longer, and fiber can help prevent constipation.Where to find it: apples, pears, oatmeal, Brussels sprouts, oat bran, almonds.
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Expression Level Of Apoa
To compare the expression level of apoA-I in HDL, the same amount of total proteins per individual HDL was loaded on each lane of a gel. As shown in Figure Figure2,2, the slim group showed 2.2- and 1.3-fold higher expression levels of apoA-I in HDL2 and HDL3, respectively, compared to the plump group as determined by SDS-PAGE. Based on Western blotting with an apoA-I antibody, the slim group showed 1.5- and 1.6-fold higher apoA-I levels in HDL2 and HDL3, respectively, compared to the plump group.
Diet For High Triglycerides: What To Eat And What Not To Eat
A key role in the management of high triglycerides can play it there diet. With the exception of those conditions deriving from underlying pathologies, for which the attending physician will be the most suitable reference, nutrition will be fundamental.
Anyone suffering from high triglycerides will need to pay special attention to both foods to avoid that to the recommended foods.
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Where Does Cholesterol Come From
Cholesterol comes from 2 sources:
It is produced in the liver and distributed throughout the body via the bloodstream.
The second source is dietary cholesterol that makes a much smaller portion of the cholesterol found in your blood. This cholesterol generally comes from animal products, ie. shellfish, meat from organs, egg yolk and dairy products.
Studies are beginning to show that dietary cholesterol may actually play a much smallerrole in raising your blood cholesterol levels than previously thought. More research is currently being conducted in this area of interest however.
What Is The Difference Between Good And Bad Cholesterol
You may have heard that there are both good and bad forms of cholesterol. This is true, but its often confusing to know which is which and why one is good vs. bad.
Lets clear that up:
Lipoproteins are the proteins on which cholesterol travels through the blood.
A High Density Lipoprotein absorbs the cholesterol and delivers it to the liver. Once the liver receives it, it flushes the cholesterol from the body. This is considered the good form of cholesterol, because it can reduce the risk for stroke and heart disease.
An excessive amount of Low Density Lipoprotein can build plaque on the walls of blood vessels, which has the potential to dangerously block the blood flow to the heart. This can increase the risk for stroke and heart disease. Hence, why its thought of as the bad cholesterol.
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How Cholesterol Moves Around The Body
Cholesterol is a white, insoluble and waxy substance. It is carried around the body by two key transport systems in the blood, which include:
- Low-density lipoprotein cholesterol carries most of the cholesterol that is delivered to cells. It is called the bad cholesterol because when its level in the bloodstream is high, it can clog up your arteries.
- High-density lipoprotein cholesterol is called the good cholesterol, because it helps remove excess cholesterol out of the cells, including cells in the arteries.
What Causes High Cholesterol In Thin People
Many patients are surprised when their doctors inform them that they have high cholesterol because they are very young, their bodies look very thin, they do not feel fat at all like the pictures of people with high blood fat on television.
8/2/2021 11:16:49 PM
About 25% of people with a normal BMI have cardiovascular problems such as high blood pressure, dyslipidemia, and hyperglycemia.
Here are five essential points to identify these patients:
1. BMI is not as important as the location of fat storage
– New visceral fat is closely associated with cardiovascular disease. A waist circumference > 94cm in men and > 80cm in women is a simple way to detect this problem.
2. Muscle/fat mass is more important than the total mass
– These people often have instead “flabby” muscles examine the biceps , the calves are often very little muscle. The waist area is full of fat, and the abdominal muscles are loose. Most are office workers or sedentary women.
3. Unhealthy Diet
Being thin doesn’t mean eating healthy. Don’t eat fatty meat, but eat a lot of beef, offal, canned food, eat vegetables but have to fry with fat, but rarely eat boiled vegetables. Or those of you who lose weight with carbohydrates such as fasting for breakfast only eat sweet potatoes but drink milk, tea and soft drinks. Due to their nutrient absorption characteristics, these people will absorb more fat and sugar, store fat around the viscera and build less muscle.
5. Family factor
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Good Cholesterol Versus Bad Cholesterol
Cholesterol is carried through your body on two different types of proteins:Low-density lipoprotein , or bad cholesterol. This type of cholesterol contributes to fatty buildups in your arteries. If you have too much LDL, you could be at greater risk for heart attack, stroke, and peripheral artery disease.
High-density lipoprotein , or good cholesterol. It is believed that the HDL in your blood carries the LDL away from your artery and back to your liver, where it is broken down and passed out of the body.
When your doctor tests your cholesterol, theyll measure the total cholesterol, as well as your levels of LDLs and HDLs, and then make recommendations based on these numbers.
Even if youre not worried about your cholesterol but want to improve your heart health, the tips below are a good start!
Beyond Statins: Managing High Cholesterol And Triglycerides
High cholesterol is an extremely common problem, affecting as many as 93 million people over age 20 in the United States , according to the Centers for Disease Control and Prevention . But because high cholesterol has no symptoms and can only be detected with a blood test, many people may not realize they have it.
High cholesterol and its close cousin high triglycerides another type of fat, or lipid, in your blood can increase your risk for heart disease and stroke, which is a problem because theyre leading causes of death in the U.S., according to the American Heart Association .
Everyone really needs to pay attention, because if they dont have high cholesterol, they probably know someone who does, says Partha Nandi, MD, host of the Dr. Nandi Show and chief health editor of WXYZ-TV ABC Detroit. Whats key is that you have to get your cholesterol checked.
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Myth: I Cant Do Anything To Change My Cholesterol Levels
Fact: You can do many things to improve your cholesterol levels and keep them in a healthy range!
- Get tested at least every 5 years .1,2 Learn more about cholesterol screenings.
- Make healthy food choices. Limit foods high in saturated fats. Choose foods naturally high in fiber and unsaturated fats. Learn more about healthy diets and nutrition at CDCs nutrition, physical activity, and obesity website.
- Be active every day. The Physical Activity Guidelines for Americans recommends that adults get 150 to 300 minutes of moderate physical activity each week. Learn more about physical activity basics and tips.
- Dont smoke or use tobacco products. Smoking damages your blood vessels, speeds up the hardening of the arteries, and greatly increases your risk for heart disease. If you dont smoke, dont start. If you do smoke, quitting will lower your risk for heart disease. Learn more about tobacco use and ways to quit at CDCs smoking and tobacco use website.
- Talk with your health care provider about ways to manage your cholesterol if any medicines are given to you to manage your cholesterol, take them as they are prescribed. Learn more about medicines to lower cholesterol.
- Know your family history. If your parents or other immediate family members have high cholesterol, you probably should be tested more often. You could have a condition called familial hypercholesterolemia .
How To Lower High Ldl Cholesterol
Your doctor will set up a plan of lifestyle changes and/or medication that can lower your cholesterol levels and your overall odds of a heart problem. Your plan might include:
- A healthy diet. Try not to eat things that are high in saturated fat, cholesterol, or simple carbs such as sugar and white flour. Eat more fiber and plant sterols such as margarine or nuts.
- Regular exercise. The kind that gets your heart pumping is best.
- Weight loss. Losing even 5 to 10 pounds can improve your cholesterol levels.
- Quitting tobacco. If you have a hard time giving up smoking, your doctor can help you find the program thatâs best for you.
- Medication. Some drugs, like statins, help keep your body from making cholesterol. Another, ezetimibe , lowers the amount of cholesterol your body gets from food you eat. If you canât take statins or have a severe form of high cholesterol, you might get shots of PCSK9 inhibitors. These meds help your liver remove more LDL from your blood.
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What Causes High Cholesterol
Lots of different things play a part in your cholesterol levels , and these can all add up. Many of the things which raise your cholesterol raise your risk of heart disease too, so the steps you take to lower your cholesterol will also lower your risk of heart disease.
- not being physically active.
Your age, gender and family background
Other things you can’t change can mean youre more likely to develop high cholesterol and heart disease:
- your age raised cholesterol and damaged arteries become more likely with age
- being male men are more likely to have high cholesterol and heart attacks than women
- being from a South Asian background
- family history a close family member, such as a parent, brother or sister, has had high cholesterol, heart disease or a stroke.
High cholesterol can be genetic, meaning you inherit it from your parents:
- Familial hypercholesterolaemia can cause very high cholesterol, even if you have a healthy lifestyle.
- There are other genetic conditions too.
Your overall health
Misconception: If The Nutrition Facts Label Shows No Cholesterol The Food Is Heart Healthy
A foods Nutrition Facts label can be helpful for choosing heart-healthy foods, if you know what to look for.
Many foods marketed as low-cholesterol have high levels of saturated or trans fats, both of which raise blood cholesterol.
Look for how much saturated fat, trans fat and total calories are in a serving. Ingredients are listed in descending order of use, so choose products where fats and oils are near the end of the ingredients list.
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