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Medication For High Triglycerides And Cholesterol

Will A Keto Diet Lower Triglycerides And Cholesterol

High Cholesterol – Do I Need To Take Medication?

No, keto diets have been shown to increase cholesterol levels. The Mediterranean diet, however, has been shown to lower cholesterol levels and reduce the risk of cardiac events.

The Mediterranean diet promotes eating vegetables, fruits, whole grains, and healthy fats daily eating fish, poultry, beans, and eggs weekly reducing portions of dairy and limiting red meat.

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Effect Of Niacin On Cardiovascular Outcomes

MONOTHERAPY

COMBINATION WITH FIBRATES

In the Stockholm Ischemic Heart Disease Secondary Prevention Study survivors of a myocardial infarction below 70 years of age were randomized to a control group and a group treated with clofibrate and immediate release nicotinic acid . Serum cholesterol and TG was lowered by 13% and 19%, respectively, in the treatment group compared to the control group. Recurrent myocardial infarction was reduced by 50% within one year . Total mortality was decreased by 26% in the group treated with clofibrate + niacin while ischemic heart disease mortality was decreased by 36% . Notably, the benefit of clofibrate + niacin was only observed in patients with a baseline TG level > 143mg/dl. In the age of statins, the clinical implications of this early study are unclear.

COMBINATION WITH STATINS

Mechanism Accounting For The Omega

While not the primary mechanism for the decrease in plasma TGs, studies have shown that omega-3-fatty acids may increase the clearance of TG rich lipoproteins . Post heparin lipoprotein lipase activity is not increased by omega-3-fatty acid administration but the lipolytic activity of non-stimulated plasma is enhanced . Additionally, apolipoprotein C-III levels are decreased with omega-3-fatty acid administration which could also contribute to an increase in the clearance of TG rich lipoproteins .

The increase in LDL-C levels that occurs in patients with marked hypertriglyceridemia treated with omega-3-fatty acids is thought to be due to the enhanced conversion of VLDL to LDL .

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What Can You Do At Home To Treat High Triglycerides

The main way to deal with high triglycerides is to eat better and get more exercise. Here are some guidelines to help you manage your level:

Moderate exercise: Try to exercise 5 or more days each week. Lack of movement makes it hard for your body to process blood sugar and triglycerides as it normally does. So itâs important for you to get up and get moving more each day. Skip the escalator or elevator and climb stairs. Get off the bus or subway one stop early and walk. Find activities you enjoy: Walk, swim, or ride a bike. Join a gym. Talk to your doctor before you begin any exercise plan.

Watch your weight: If youâre carrying extra pounds, losing 5% to 10% of your weight can lower triglycerides. People with a healthy weight are more likely to have normal levels. Belly fat is associated with higher numbers.

Eat less bad fat and carbs: Try to lower the saturated fat, trans fat, and cholesterol in your diet. Cutting back on carbohydrates will help, too. Foods high in saturated fat, such as red meat, boost levels. Butter and cheese contain these same triglyceride-boosting fats. Choose lean meats or protein alternatives, such as chicken and unprocessed turkey, that are lower in saturated fat.

Another healthy option: Make meatless meals. Vegetarian pastas, chilis, and stir-fries are a delicious alternative to meat dishes. Avoid dishes loaded with cream or cheese in favor of recipes that use vegetable or olive oil and feature plenty of vegetables.

Reduce Your Intake Of Saturated And Trans Fats

Best Ayurvedic Medicines For High Cholesterol

Adopt and follow a healthy diet thats low in saturated and trans fats. A diet high in these fats can raise levels of LDL cholesterol in the blood.

Saturated fat is usually solid at room temperature. Its found in animal products such as meat and dairy, but also in palm oil, coconut oil and full-cream milk. Read more about saturated fat-rich foods here.

Trans fats are found in store-bought baked goods, snack foods and deep-fried foods. There is strong evidence that trans fats increase levels of LDL cholesterol in the blood, while decreasing levels of HDL cholesterol.

Some foods contain cholesterol . Foods that contain cholesterol include liver, pate, kidneys, prawns and egg yolks. These types of food are not usually eaten in large quantities, so its OK to include them in your diet in small amounts.

Foods that contain saturated fats have a greater effect on blood cholesterol levels than foods that contain dietary cholesterol.

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What Are Normal And High Triglyceride Levels

The National Cholesterol Education Program sets guidelines for triglyceride levels:

  • Normal levels: Less than 150 milligrams per deciliter
  • Borderline high:150 to 199
  • High: 200 to 499
  • Very high: 500 or more

Elevated levels may lead to heart disease, especially in people with low levels of “good” cholesterol and high levels of “bad” cholesterol. The same is true if you have type 2 diabetes.

Experts once debated how important triglycerides are, but it now seems clear that higher levels are linked to problems such as heart disease.

One thing is clear, though: A good diet and exercise plan can lower triglyceride levels, improve cholesterol, and decrease the chance of heart disease.

What Causes High Triglycerides

Aside from consuming a high-fat and/or high-carb diet, other lifestyle factors can contribute to high triglycerides, specifically excess weight, lack of exercise, drinking too much alcohol and smoking. Dr. Malaney adds that it can also be a side effect of certain medications, such as some birth control pills, beta blockers, antipsychotics medications, and corticosteroids.

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Triglycerides And Cholesterol: What Are High Levels And How To Lower Them To Avoid Heart Disease

In Argentina, only one in three cardiac patients meets the goals of cholesterol control established by the Argentine Society of Cardiology . The data is even more worrying for patients with very high cardiovascular risk, since in this group the level of monitoring decreases to 16%. The high cholesterol -o hypercholesterolemia is one of the so-called silent diseases. It does not cause symptoms, pain or warning signs.

Cholesterol is onefatty substance It is present in all tissues of the human body and is necessary for the normal functioning of the organism. It serves as raw material for cell membranes and for the synthesis of hormones such as estrogens and androgens.

Then, cholesterol is not an enemybut in excess it generates serious consequences for health by increasing the probability of cardiovascular disease. There are other lipid substances in the blood in addition to cholesterol. Among them are the triglycerideswhose elevation also increases the risk of heart conditions.

The cardiologists at Mayo Clinicin the USA, describe the differences between these two types of lipids that circulate in the blood:

Los triglycerides store unused calories and provide energy to the body

The cholesterol is used to build cells and certain hormones

These lipoproteins that remove cholesterol are called HDL , it is popularly known as good cholesterol. Other lipoproteins transport cholesterol from the liver to the rest of the organs. These are called LDL .

KEEP READING:

What Are Triglycerides And What Is Considered A Healthy Level

Pharmacology – DRUGS FOR HYPERLIPIDEMIA (MADE EASY)

Triglycerides are sort of like cholesterol: Both are types of fat found in your blood. But while cholesterol is used to make cells and certain hormones, the job of triglycerides is to store unused calories to give your body energy between meals.

Triglycerides get stored after you eat. If you take in any calories that arent needed for energy right away, theyre converted into triglycerides and transferred to your fat cells for later use.

Eating more calories than you need on the reg can lead to high triglycerides over time, which can up your risk for heart disease. Triglycerides are usually measured along with cholesterol, and numbers over 150 mg/dL are usually considered high.

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Develop Healthy Sleep Habits

Sleeping too little is common but detrimental to your health. In fact, loss in sleep is associated with increased cholesterol levels and related problems, such as high triglycerides and blood pressure. To improve your sleep, aim for consistent bed and waking times, sleep in a cool, dark, comfortable room, and avoid stimulating activities, such as working on a computer, before bed.

Effect Of Fibrates In Combination With Other Lipid Lowering Drugs On Lipid And Lipoprotein Levels

STATINS

Statins are the primary drugs used to treat most patients with dyslipidemia. Statins are very effective in lowering LDL-C levels but have only modest effects on TG and HDL-C levels. Therefore, it is appealing to add a fibrate to patients who on statin therapy have LDL-C levels at goal but still have elevated non-HDL-C and TG levels and decreased HDL-C levels. Therefore, there have been numerous studies examining the effect of the combination of statins and fibrates on lipid and lipoprotein levels. An example is the Safari Trial which compared the effect of simvastatin only vs. simvastatin + fenofibrate in patients with combined hyperlipidemia . The results of this trial are shown in . As anticipated, adding a fibrate results in a further lowering of LDL-C, non-HDL-C, and TG levels with a further increase in HDL-C.

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Health Conditions Related To Triglycerides And Cholesterol

High blood lipid levels may increase your risk for plaques to develop in your arteries or thicken the walls of your arteries .

Other health conditions related to high triglycerides or cholesterol include:

  • High blood sugar levels or diabetes
  • Metabolic syndromea cluster of conditions that increase your risk for heart disease
  • Genetic conditions

How To Lower Cholesterol And Triglycerides

Clotgone for cholesterol

Triglycerides are a type of lipid, or fat, your body produces to store extra calories and provide energy. Cholesterol is another lipid that circulates in your blood. Your body uses cholesterol to build cells and produce hormones.

Both triglycerides and cholesterol are essential for your health but having levels that are too high puts your health at risk. Living a healthy lifestyle helps to keep your cholesterol and triglyceride levels within a normal range.

This article covers how triglycerides and cholesterol affect your health and how you can lower them naturally.

Luis Alvarez / Getty Images

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How To Lower Triglycerides Fast Without Medications

Unlike many illnesses, much of the treatment centered around how to lower triglycerides actually has a lot to do with lifestyle factors like diet and physical activity. In fact, moderate to slightly high levels of triglycerides may be managed in this way alone, without the use of prescription medications. Since what raises triglycerides in the first place is often the foods that we eat, it is not a wonder that a mere change in ingestibles can provide long term benefits in the form of lower triglycerides levels. And, the long term management of the amounts of these fats circulating in the blood can often be well managed with a diet to lower triglycerides combined with an increase in moderate exercise.

Fats are also best left alone as much as possible for anyone trying to stave off ever rising levels of the manufactured blood fats. As such, fried foods and those that contain trans fat or saturated fat should be eliminated from diets entirely. Not only does this decrease the likelihood that triglycerides will remain on the rise, a low fat diet also contributes to a reduced risk of obesity. Being overweight or obese is a major contributing factor to the increase of triglycerides in the blood, and adhering to a low fat diet can reduce this risk dramatically.

References:

How Is A Lipid Disorder Diagnosed

To check your cholesterol levels, your doctor will order a blood test called a lipid profile, or lipid panel. This test measures your total cholesterol and triglycerides. Before this test, your doctor will likely ask you to avoid eating and drinking liquids other than water for at least 8 to 12 hours.

The lipid profile measures cholesterol in milligrams of cholesterol per deciliter . Your total cholesterol level should be no higher than 200 mg/dL. Learn how to understand your cholesterol results.

A combination of medications and lifestyle changes is a common treatment plan to correct high cholesterol and triglycerides. Your doctor may also suggest certain supplements.

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Diets High In Calories Carbs And Fats

Triglyceride levels increase with a positive energy-intake balance . In other words, when you eat more than your body needs, the surplus is transformed into fat, including triglycerides. Its easier to overeat when your diet is high in calories and contains lots of carbs and saturated fats .

Low-fat, high-carbohydrate diets are among the most common causes of high triglycerides. But wait we said that high-fat diets are bad, so doesnt that mean a low-fat diet should be beneficial? Not quite .

Saturated, unhealthy fats are bad. But your body needs healthy fats such as those found in olive oil and fish oil to keep your triglyceride levels normal and to maintain your overall health. If you dont get enough dietary fats, your body will revert to transforming the sugars you consume into fats .

This goes against the popular but unfounded belief that your body wont store fat as long as you dont eat fats. In truth, high-carbohydrate diets can be much worse than high-fat diets for your triglyceride levels. Many scientists advocate that high-carb, low-fat diets likely also contributed to the obesity epidemic in America over the past few decades .

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Is It Possible To Lower Triglycerides Naturally

Cholesterol and Triglycerides

Similar to cholesterol, triglycerides come from the food we eat and our liver. When levels are normal, triglycerides are used for energy. The problems arise when levels are high, explains Dr. Nissen. When we make more triglycerides than we use, the rest are stored as fat. Thats why many people who are overweight or have type 2 diabetes have high levels.

Poor diabetes control is a major factor in causing high triglyceride levels, Dr. Nissen says. He stresses the importance of watching your carbohydrate consumption. Eating a low-carb diet and getting plenty of exercise are often effective in lowering triglyceride levels.

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How Are Fats And Cholesterol Connected In Cats

Fats, including cholesterol, are carried in the blood in complex compounds that also contain protein: so-called lipoproteins.

These include triglycerides, cholesterol and phospholipid linked to apopproteins, which are manufactured in cells of the liver and intestines. Apolipoproteins are synthesized in the liver or in intestinal cells.

There are four major lipoprotein classes in cats, as follows:

Chylomicrons and Very low density lipoproteins carry triglycerides in the blood

Low density lipoproteins and High density lipoproteins carry cholesterol in the blood. In cats, HDL outnumbers LDL by 5:1, while in humans, LDL is the main carrier of cholesterol.

Many humans are aware of these abbreviations from their own blood test results, but its important to remember that the significance of abnormal levels is very different in humans compared to cats.

How To Lower Triglycerides

Your doctor will determine if you need treatment to lowering triglycerides by talking with you about your current diet and lifestyle, and evaluating your triglyceride level, your LDL cholesterol level, and your potential risk factors for coronary heart disease.

Here are some of the reasons your doctor might discuss medications to lower triglycerides with you:

  • You have metabolic syndrome. This condition includes a combination of abdominal obesity, high triglycerides, and high blood pressure. If you have metabolic syndrome and tried diet and lifestyle changes for three months without success, triglyceride-lowering medications may be needed.
  • Previous medication lowered your total cholesterol but not your triglycerides. If your cholesterol is well controlled, but your triglyceride level is still too high, at or above 200 mg/dL, triglyceride-lowering medications may help.
  • You have very high triglycerides. If your triglyceride level is at or higher than 500 mg/dL, you may need to start medications to lower triglycerides even before reaching lower cholesterol levels.

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Eat Fatty Fish Twice Weekly

Fatty fish is well known for its benefits on heart health and ability to lower blood triglycerides.

This is mostly due to its content of omega-3 fatty acids, a type of polyunsaturated fatty acid that is considered essential, meaning you need to get it through your diet.

Both the Dietary Guidelines for Americans and American Heart Association recommend eating two servings of fatty fish per week to reduce the risk of heart disease and stroke .

Whats more, one study showed that eating salmon twice a week significantly decreased blood triglyceride concentration .

Salmon, herring, sardines, tuna, and mackerel are a few types of fish that are especially high in omega-3 fatty acids.

Summary

Fatty fish is high in omega-3 fatty acids. Eating two servings per week may lower triglyceride levels and decrease the risk of heart disease.

What To Eat: Foods That Lower Cholesterol

Many of the same lifestyle changes and medications can lower both ...

There is great evidence to support functional foods that help lower cholesterol, Featherstun says. Add these choices to your diet:

Plant stanols and sterols These are naturally occurring compounds found in plant cell walls, Featherstun says. They interfere with cholesterol absorption in the small intestine and can help lower LDL cholesterol. A study published in October 2012 in Lipids in Health and Disease found that eating 9 to 10 grams of stanols per day can help lower LDL cholesterol by more than 17 and as much as 22 percent. You can get plant stanols and sterols in margarine-like spreads such as Benecol and Smart Balance, available in the dairy section of most grocery stores.

Monounsaturated and polyunsaturated fats These fats can help decrease LDL cholesterol, Featherstun says. To get them, eat fish high in omega-3 fatty acids, such as salmon, tuna, trout, herring, or king mackerel, at least twice a week. Other good sources of unsaturated fats include chia seeds, avocados, almonds, walnuts, and olive oil.

Soy foods Soy proteins contain isoflavones and phytoestrogens, which block both cholesterol absorption and new cholesterol production, Featherstun says. Good sources of soy protein include tofu, soy milk, and edamame. Try to replace one daily animal protein item with a soy protein alternative, Featherstun suggests.

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