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Is There Medication For High Triglycerides

How Can Triglyceride Levels Be Lowered

High Triglycerides (Part 1) – Medication vs. Lifestyle – Eicosapent Ethyl

If your triglyceride levels are high, the next step is for your doctor to check for potential causes. Certain medications, thyroid function issues, poorly controlled diabetes, liver or kidney disease can all cause triglyceride levels to be higher than normal.

The first steps in treatment to lower triglyceride levels include eating a healthy diet, achieving and maintaining a healthy weight, and aerobic exercise on a regular basis.

To lower your triglyceride levels, your diet should be:

  • low in simple carbohydrates

If you have high triglycerides and low HDL or high LDL levels, you may need to take medication along with making lifestyle changes. If your triglyceride levels are in the very high range you are at risk to develop other medical problems, so you will most likely need to take medication.

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My Cholesterol Is Normal But My Triglycerides Are High: Why Is That

So both your HDL and LDL levels are where they should be, but your triglycerides are still high why is that?

Triglycerides become elevated due to excess calories that do not get burned off, and in turned get stored in fat cells. Statins are medications that primarily lower LDL cholesterol, but depending on the medication dose, can lower Triglycerides from 20 to 40 percent, Sai Hanumanthu MD, with the TriHealth Heart Institute explains.

There are steps you can take to lower your triglyceride levels while promoting good cardiovascular health, including:

  • Losing 5 to 10 pounds if overweight
  • Avoiding alcohol
  • Avoiding foods high in saturated fats
  • Limiting simple carbs that have high processed sugars .
  • Participating in 30 minutes of exercise per day

All these suggestions and routine follow up with a medical professional will lower you triglyceride level, even despite a low total cholesterol, Dr. Hanumanthu says.

Effect Of High Dose Omega

It should be noted that in this trial mineral oil was used as the placebo. In the placebo group the LDL-C, non-HDL-C, and CRP levels were increased during the trial . The impact of these adverse changes on clinical outcomes is uncertain and whether they contributed to the apparent beneficial effects observed in the individuals treated with EPA is unknown.

4) The OMEMI trial was a randomized trial of 1.8 grams per day of omega-3-fatty acids vs. corn oil placebo in patients aged 70 to 82 years with a recent myocardial infarction . Baseline LDL-C was approximately 76mg/dL, HDL-C was 49mg/dL, and TGs 110mg/dL. The primary endpoint was a composite of nonfatal myocardial infarction, unscheduled revascularization, stroke, all-cause death, and heart failure hospitalization after 2 years of follow-up. The primary endpoint occurred in 21.4% of patients on omega-3-fatty acids vs. 20.0% on placebo . TGs levels decreased 8.1% in the omega-3-fatty acid group and increased 5.1% in the placebo group while changes in LDL-C were minimal in both groups. Thus, similar to the STRENGTH trial no benefits on cardiovascular disease were observed with EPA + DHA treatment.

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A Sign Of Metabolic Syndrome

People with metabolic syndrome are several times more likely to have a heart attack or stroke. The risk of eventually developing diabetes is even greater.

A syndrome is, by definition, a group of signs and symptoms that occur together because of an underlying condition. For metabolic syndrome, that group includes abdominal obesity , high blood pressure, high blood sugar, low HDL cholesterol and, yes, levels.

So as doctors have started to take metabolic syndrome more seriously, they’ve also started to pay more attention to triglyceride levels as one of its telltale signs.

Triglycerides go it alone

HDL and triglycerides are metabolically connected and are often inversely related: As triglycerides go up, HDL goes down and vice versa. But that isn’t always so. People can have “isolated” high triglycerides without low HDL levels, and research is now showing that high triglycerides are an independent risk factor for cardiovascular disease, no matter what the HDL is.

Will A Keto Diet Lower Triglycerides And Cholesterol

Cholesterol &  Triglycerides Support, 60 Capsules

No, keto diets have been shown to increase cholesterol levels. The Mediterranean diet, however, has been shown to lower cholesterol levels and reduce the risk of cardiac events.

The Mediterranean diet promotes eating vegetables, fruits, whole grains, and healthy fats daily eating fish, poultry, beans, and eggs weekly reducing portions of dairy and limiting red meat.

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Effect Of Fibrates On Cardiovascular Outcomes

There have been a number of studies that have examined the effect of a variety of different fibrates on cardiovascular disease. We will describe the major studies below.

A separate meta-analysis has focused on the effect of fibrates on cardiovascular disease in patients with pre-existing disease . It included 13 trials involving a total of 16,112 participants. For the primary composite outcome of non-fatal stroke, non-fatal myocardial infarction, and vascular death, fibrate therapy significantly decreased risk by 12% 0.88, 95% 0.83 to 0.94). Fibrates were effective for preventing myocardial infarction . Fibrates were not effective in lowering all-cause mortality , death from vascular causes , or stroke events . Since clofibrate has been discontinued due to safety concerns, the data were reanalyzed excluding clofibrate trials. Without clofibrate, fibrates no longer significantly reduced the primary outcome but were still effective in preventing myocardial infarctions . Subgroup analyses showed the benefit of fibrates on the primary composite outcome to be consistent irrespective of age, gender, and diabetes mellitus.

SUMMARY OF OUTCOME STUDIES

How Are Fats And Cholesterol Connected In Cats

Fats, including cholesterol, are carried in the blood in complex compounds that also contain protein: so-called lipoproteins.

These include triglycerides, cholesterol and phospholipid linked to apopproteins, which are manufactured in cells of the liver and intestines. Apolipoproteins are synthesized in the liver or in intestinal cells.

There are four major lipoprotein classes in cats, as follows:

Chylomicrons and Very low density lipoproteins carry triglycerides in the blood

Low density lipoproteins and High density lipoproteins carry cholesterol in the blood. In cats, HDL outnumbers LDL by 5:1, while in humans, LDL is the main carrier of cholesterol.

Many humans are aware of these abbreviations from their own blood test results, but its important to remember that the significance of abnormal levels is very different in humans compared to cats.

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What Are Triglycerides And What Is Considered A Healthy Level

Triglycerides are sort of like cholesterol: Both are types of fat found in your blood. But while cholesterol is used to make cells and certain hormones, the job of triglycerides is to store unused calories to give your body energy between meals.

Triglycerides get stored after you eat. If you take in any calories that arent needed for energy right away, theyre converted into triglycerides and transferred to your fat cells for later use.

Eating more calories than you need on the reg can lead to high triglycerides over time, which can up your risk for heart disease. Triglycerides are usually measured along with cholesterol, and numbers over 150 mg/dL are usually considered high.

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Visit Ucf Healths Cardiologist Dr Bernard Gros Who Specializes In Lipid Disorders

High Triglycerides: Is Your Medicine Causing It?? (11 Culprits)

UCF Healths Dr. Bernard Gros is a board certified cardiologist who specializes in lipid disorders like high triglycerides. Dr. Gros completed his medical degree at Emory University School of Medicine. He completed a residency in Internal Medicine at University of Michigan, followed by a fellowship in Cardiology at the same location. Dr. Gros has been with UCF Health College of Medicine since 2011, as one of the founding health care providers.

At UCF Health, our cardiologists use a collaborative care approach to serve patients in the best way possible and show you how to prevent heart disease. We strive to ensure that all members of the health care team are on board with the treatment plan and facilitate clear communication across specialties.

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Dos And Donts In Managing High Triglycerides:

  • DO exercise regularly.
  • DO eat more fruits and vegetables and high-fiber foods such as oat bran. Cook with monounsaturated fatsolive, peanut, and canola oils.
  • DO stop smoking.
  • DO lose weight by changing your diet and doing aerobic exercise, such as walking, jogging, bicycling, or swimming. Exercise at least 30 minutes daily.
  • DONT forget to treat other medical conditions such as diabetes and underactive thyroid.
  • DONT drink more than two alcoholic drinks per day.
  • DONT change your diet or medicines without your doctors approval.

Controlling High Triglycerides: Medical Treatment

People with heart disease and high triglycerides may need medication to bring down their levels.

  • Fibrates can lower triglycerides. They modestly improve cholesterol levels, too.
  • Fish oilwith omega-3 fatty acids can help keep triglycerides under control. Ask your doctor whether you should use prescription fish oil. Omega-3 acids from plant sources like flaxseed may help.
  • Niacin can lower triglycerides by up to 50%. It’s available as a non-prescription supplement and as a prescription drug.

Remember that to stay healthy and keep your triglycerides down, you still have to focus on improving your lifestyle.

When you talk to your doctor, discuss all of the medicines, supplements, and vitamins you take. Some common drugs — like beta-blockers, birth control pills, and diuretics — can cause high triglycerides as a side effect. It’s possible that one of them could be causing your problem.

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The Problem With High Triglycerides

High triglycerides are also called hypertriglyceridemia. According to the Centers for Disease Controls and Prevention , about 25 percent of adults in the US have high triglycerides over 150 milligrams per deciliter .

High triglyceride levels are often linked to liver and pancreas issues. A 2012 study published in the Indian Journal of Endocrine Metabolism has found that high triglycerides may trigger acute pancreatitis . A 2014 research published in Biomedical Reports has found that high triglycerides may increase the risk of non-alcoholic fatty liver disease .

High triglycerides along with poor cholesterol may also affect your kidneys. A 2016 study published in the Journal of Clinical Medicine has found that elevated triglycerides and low HDL cholesterol may cause kidney issues .

High triglycerides may also increase the risk of heart disease. A 2018 study published in Nutrients has found that high triglycerides may increase the risk of cardiovascular disease . However, other research, including a 2011 review published in Atherosclerosis, Thrombosis, and Vascular Biology has found that the relationship between triglycerides and cardiovascular issues is not clear. The link may be more complex and we may have to consider other factors as well.

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Reduce Your Intake Of Saturated And Trans Fats

Cholesterol &  Triglyceride Lowering Supplement for High Blood Pressure ...

Adopt and follow a healthy diet thats low in saturated and trans fats. A diet high in these fats can raise levels of LDL cholesterol in the blood.

Saturated fat is usually solid at room temperature. Its found in animal products such as meat and dairy, but also in palm oil, coconut oil and full-cream milk. Read more about saturated fat-rich foods here.

Trans fats are found in store-bought baked goods, snack foods and deep-fried foods. There is strong evidence that trans fats increase levels of LDL cholesterol in the blood, while decreasing levels of HDL cholesterol.

Some foods contain cholesterol . Foods that contain cholesterol include liver, pate, kidneys, prawns and egg yolks. These types of food are not usually eaten in large quantities, so its OK to include them in your diet in small amounts.

Foods that contain saturated fats have a greater effect on blood cholesterol levels than foods that contain dietary cholesterol.

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What Raises The Risk For High Triglycerides

Triglycerides normally increase with age. They may become too high for one or more reasons.

Risk factors include

Most often, having high triglycerides has no warning signs. The good news, though, is there is a simple test to find high triglycerides, and treatments are available.

The most common reasons for high triglycerides include being overweight, lack of exercise, the metabolic syndrome, type 2 diabetes, and familial combined hyperlipidemia. The latter is a genetic disorder that runs in the family. It results in high triglycerides, high bad cholesterol, and low good cholesterol.

What Are High Triglycerides

Triglycerides are a kind of fat found in blood. Cholesterol is another kind. Stored in fat cells for later use, triglycerides are a major energy source. Normal amounts are important for good health. Eating more fat than the body burns can lead to high triglyceride levels . High triglyceride levels may result in hardening of the arteries , which increases risks of stroke, heart attack, and heart disease. They can be part of metabolic syndrome, which also includes too much fat around the waist, high blood pressure, high blood sugar, and abnormal cholesterol levels.

Sometimes high triglyceride levels mean poorly controlled type 2 diabetes, low thyroid hormone levels , liver or kidney disease, or rare genetic conditions.

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Know Your Triglyceride Numbers

A blood test called a lipid panel checks both your triglyceride and cholesterol levels. Usually, your doctor will ask that you fast, or not eat or drink anything other than water, for 9-12 hours before the test. Youâll get blood taken from a vein in your arm. Some labs offer non-fasting lipid panels, or they may prick your finger for blood.

Here are the levels, based on a fastingblood test.

  • Normal: Less than 150 mg/dL
  • Borderline: 150 to 199 mg/dL
  • High: 200 to 499 mg/dL
  • Very High: 500 mg/dL or above

Anyone over age 20 needs to get regular tests to track their cholesterol and triglyceride levels, according to the American Heart Association.

American Heart Association News Stories

High Triglycerides: The Latest Recommendations

American Heart Association News covers heart disease, stroke and related health issues. Not all views expressed in American Heart Association News stories reflect the official position of the American Heart Association. Statements, conclusions, accuracy and reliability of studies published in American Heart Association scientific journals or presented at American Heart Association scientific meetings are solely those of the study authors and do not necessarily reflect the American Heart Associations official guidance, policies or positions.

Copyright is owned or held by the American Heart Association, Inc., and all rights are reserved. Permission is granted, at no cost and without need for further request, for individuals, media outlets, and non-commercial education and awareness efforts to link to, quote, excerpt or reprint from these stories in any medium as long as no text is altered and proper attribution is made to American Heart Association News.

Other uses, including educational products or services sold for profit, must comply with the American Heart Associations Copyright Permission Guidelines. See full terms of use. These stories may not be used to promote or endorse a commercial product or service.

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What Are The Types Of Fibrate Drugs

There are several types of fibrates. You may take:

Last reviewed by a Cleveland Clinic medical professional on 02/10/2022.

References

  • American Heart Association. Cholesterol Medications. Accessed 2/10/2022.
  • Blais JE, Kin Yi Tong G, et al. Comparative efficacy and safety of statin and fibrate monotherapy: A systematic review and meta-analysis of head-to-head randomized controlled trials. 2021 Feb-. PLoS ONE 16: e0246480. Accessed 2/10/2022.
  • Singh G, Correa R. Fibrate Medications. Treasure Island : StatPearls Publishing 2021 Jan-. Accessed 2/10/2022.

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services.Policy

What Are The Precautions For Taking Cholesterol Medication

Looking for the best cholesterol medication means you need to know what precautions to take. Each drug has side effects like diarrhea, constipation, nausea, muscle soreness/pain/weakness, stomach pain, bloating, gas, fatigue, cramps, abdominal pain, flushing , peptic ulcers, vomiting, gout, high blood sugar, dizziness, heart palpitations, sweating, shortness of breath, chills, indigestion, belching, swelling, itching, rashes, hives, flu, and swelling of nasal passages.

Additionally, statins can negatively react when taken in combination with grapefruit juice. Injectable medications may also cause some bruising or pain on the area that was injected.

These side effects do not show up together or all at once. Most of them are also mild. To properly manage these, you need to consult with your doctor before taking any medication. Even the best cholesterol medication can only efficiently work if taken correctly, in correct dosages and amounts.

Side effects like these are the primary reason why some people including doctors prefer to go more natural on their cholesterol medication choices.

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Supplements And Medications To Lower Triglycerides

  • Fish oil, in doses of 3.5 grams of omega-3 fatty acids per day, can effectively lower triglycerides. Lower doses are ineffective,” explains says Scott Shurmur, MD, cardiologist and professor of medicine at Texas Tech University Health Science Center School of Medicine in Lubbock. When prescription medication is needed, lowering triglycerides usually starts with medication that lowers LDL cholesterol levels many of the same medications used to lower cholesterol will also lower triglycerides.
  • Statins are usually effective and well tolerated, and are the most commonly prescribed drugs to lower cholesterol. Examples include Lipitor , Crestor , Zocor , Lescol , Pravachol , and Mevacor . Severe side effects that last are rare, but side effects may include forgetfulness, abdominal pain, constipation, and muscle aches. You shouldn’t take one of these medications if you are pregnant or have active liver disease. Statins may interact with other drugs, including antibiotics and antivirals, so be sure to discuss all your medications with your doctor.
  • Fibrates like Tricor are used specifically to lower triglyceride levels. Side effects include stomach upset, gallstones, and muscle aches. You should not take fibrates if you have kidney disease or severe liver disease.
  • Some diabetes medications, Actos , for example, will also lower triglycerides, says Shurmur. However, this drug may cause or worsen congestive heart failure, warns the FDA.

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