Some Less Common Conditions
We have two kidneys, and they’re responsible for cleaning our blood by filtering out waste products which are then removed from the body as urine.
Chronic Kidney Disease . This is the name for a gradual decline in kidney function. People with CKD often have abnormal blood fats raised LDL cholesterol and triglycerides, and lower HDL cholesterol. Heart and blood vessel diseases are common in people with CKD so statins and other cholesterol-lowering treatments are recommended if you have CKD.
Nephrotic syndrome. This happens when our kidneys become leaky. It results in protein leaking into the urine. People with nephrotic syndrome often have raised levels of cholesterol and triglycerides too.
The liver is a very important organ. It is where cholesterol and triglycerides are processed, made or broken down. Bile, a breakdown product of cholesterol, is made in the liver, stored in the gall bladder and released into the gut when we eat a meal. Its role is to help break down fat from food into small drops which can then be easily digested.
Sometimes the production of bile or its release into the gut can become blocked, for example, if gall stones develop from crystallised cholesterol. Symptoms include pain, especially after a fatty meal. The medical name for this is cholestasis, where bile is unable to flow from the liver, and it can cause blood cholesterol levels in the blood to rise.
The Terrible Triad What Is The Role Of Vitamin D In Subclinical Hypothyroidism And Cardiovascular Risk
A September 2021 paper looked at how vitamin D deficiency and autoimmune thyroid diseases may play a role in cardiovascular disease.
The role of thyroid hormones in the cardiovascular system, through several direct and indirect effects is recognized. Even very small modification in thyroid hormone levels may adversely affect the cardiovascular system, whereas thyroid hormones benefit the cardiovascular system and improve the prognosis.
There is also evidence of vitamin D effects on cardiometabolic disease , renin-angiotensin-aldosterone system , nitric oxide, oxidative stress, and inflammatory response), as well as an association between vitamin D deficiency and autoimmune thyroid diseases or cancer, and a relationship between vitamin D concentration and titers of antibodies and thyroid autoimmunity replacement.
Interestingly, experimental data indicate a direct effect of vitamin D on Type 2 deiodinase expression causing subsequential peripheral conversion of T4 into T3. However, the functional links among thyroid hormones, vitamin D and the cardiovascular system, and clinical effects of coexisting abnormalities in this new troublesome triad, have not yet been reviewed.
Look Out For Perchlorates
Perchlorates are odorless, colorless salts that dissolve in water and are found naturally in certain parts of the United States. Theyre mainly manufactured for explosives, fireworks, and rocket motors, and theyve contaminated the water supplies in areas throughout the nation.
Because a large percentage of U.S. produce is irrigated with perchlorate-contaminated water, perchlorate is also prevalent in the U.S. food supply and many Americans are exposed to low levels, according to the Centers for Disease Control and Prevention .
Since high levels of perchlorates may reduce your thyroid hormone levels by blocking your thyroid from taking up iodine, which it needs to produce thyroid hormones, its sensible to stay up on your areas perchlorates contamination and maximum state levels for perchlorates in the water. Also, if you use well water, consider having it tested for perchlorates contamination.
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No Two Patients With Hashimotos Are The Same
There are so many toxins were exposed to, and its impossible to not only test for all of them but to understand how each individual reacts to the specific toxin. Two patients being exposed to the same toxins can have a very different response. This is why in my practice, I rely very heavily on testing. Where some Holistic practitioners only look at hormones or the adrenal glands, these areas may not be the primary triggers. They might be secondary or Tertiary problems. Contributing triggers but just not the MAIN ones.
Another reason why antibodies might remain elevated comes down to time.
Think of an Autoimmune disease like a pendulum that swings from one side to the next. Once it build up enough momentum, it just doesnt stop because you decided your going to eat and autoimmune diet protocol and take some supplements for a couple of months. I get thousands of emails every year from patients who are literally at their wits end. They say I dont understand Dr Hagmeyer I have eliminated gluten and I have been doing everything and I still feel lousy!If your immune system has been chronically activated by certain chemical mediators and the one that comes to mind is NF kappa B- your not going to shut this down overnight-Its going to take time.
#2 Remove the Autoimmune Triggers that you have Identified with testing and finally work with a physician who understands how to
#4- Chose a doctor who will lead you down the right path.
Hypothyroidism And Cholesterol: Should This Matter To Me
First and foremost, you should discuss your thyroid status and any concerns you have about your cholesterol levels and cardiovascular health with your doctor, if you havent already. While the thyroid replacement medication, levothyroxine, is effective in reversing thyroid-related hyperlipidemia in overt hypothyroidism, there is a lack of consensus regarding whether or not to treat hyperlipidemia in patients with subclinical hypothyroidism.
According to Dr. Pearce, Treatment of subclinical hypothyroidism can be considered in patients with hyperlipidemia, particularly if there are other reasons to treat. For example, the presence ofhypothyroid symptoms. However, there is currently not strong evidence for prescribing thyroid replacement in these patients otherwise.
Dr. Gabriel Brenta recommends treating with levothyroxine in those patients with hypercholesterolemia and subclinical hypothyroidism provided they are below 65 years of age. Her recommendation matches the Clinical Practice Guidelines for Hypothyroidism in Adults Cosponsored by the American Associate of Clinical Endocrinologists and the American Thyroid Association.6 Dr. Brenta and her team also recommend that levothyroxine replacement therapy may be considered for patients with persistently mildly elevated TSH levels and confirmed Hashimotos thyroiditis.
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Why Borderline High Cholesterol Is Healthy
The truth is that your borderline high cholesterol might be healthier than you think.
The current recommendations for cholesterol state the following
- 200 mg/dL or lower = Desirable Cholesterol.
- 200 mg/dL to 239 mg/dL = Borderline High.
- 240 mg/dL or above = High
But what does the research say?
Its important that we look beyond just heart disease and look at all-cause mortality.
Otherwise, as shown above, you might just be trading heart disease for cancer.
And we both know that doesnt solve any problems.
Based on all-cause mortality studies, optimal cholesterol with lowest all-cause mortality is actually 200 mg/dL to 240 mg/dL .
In other words people who are healthiest and live the longest are the ones who are considered to have Borderline High cholesterol.
This is very important to take into consideration before blindly accepting cholesterol lowering drugs from your doctor, just to be on the safe side or before you try that cholesterol lowering diet thats supposed to be so healthy for you.
Is trying to force your cholesterol lower the best thing for you?
Are you just trading heart disease for cancer or some other unnecessary cause of early death?
Or should you start by fixing the real underlying cause of the problem and focus on your thyroid health?
If you have high cholesterol due to a thyroid hormone deficiency, or low cholesterol due to liver dysfunction, the right diet can make all the difference.
So tell me
What Is The Link Between The Thyroid And Cholesterol
The thyroid is a very important gland in our bodies that releases hormones to help control metabolism. The hormones that the thyroid releases help in regulating our breathing, heart rate, body weight, muscle strength, body temperature, menstrual cycles in women, nervous system, and more. When the thyroid is not producing the correct number of hormones that we need, our bodies may feel out of whack, producing a host of symptoms.
One of the most important systems that the thyroid affects is the bodyâs ability to metabolize, causing poor processing of cholesterol. As the body changes and slows with an under active thyroid, the bodyâs inability to break down LDL may also slow, causing cholesterol to continue to build up.
There is a linear relationship seen with cholesterol and Thyroid Stimulating Hormone levels. The higher the TSH, the higher the LDL and the lower the HDL. Even when TSH is in the normal range, but on the upper limits of normal, cholesterol may be mildly elevated.
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Are There Different Types Of Thyroid Removal Surgery
If your healthcare provider determines that your thyroid needs to be removed, there are a couple of ways that can be done. Your thyroid may need to be completely removed or just partially. This will depend on the severity of your condition. Also, if your thyroid is very big or has a lot of growths on it, that could prevent you from being eligible for some types of surgery.
The surgery to remove your thyroid is called a thyroidectomy. There are two main ways this surgery can be done:
- With an incision on the front of your neck.
- With an incision in your armpit.
The incision on the front of your neck is more of the traditional version of a thyroidectomy. It allows your surgeon to go straight in and remove the thyroid. In many cases, this might be your best option. You may need this approach if your thyroid is particularly big or has a lot of larger nodules.
Alternatively, there is a version of the thyroid removal surgery where your surgeon makes an incision in your armpit and then creates a tunnel to your thyroid. This tunnel is made with a special tool called an elevated retractor. It creates an opening that connects the incision in your armpit with your neck. The surgeon will use a robotic arm that will move through the tunnel to get to the thyroid. Once there, it can remove the thyroid back through the tunnel and out of the incision in your armpit.
- Are not at a healthy body weight.
- Have large thyroid nodules.
- Have a condition like thyroiditis or Gravess disease.
Top Tips To Lower Your Cholesterol
- Maintain a healthy body weight.
- Quit smoking.
- Heart healthy diet:
Fibre: As I am sure you have heard over and over eat more fibre!!! Fibre is so important in the diet for a variety of reasons and one of them being its heart healthy properties and ability to reduce cholesterol. Gluten free high fibre cereal for breakfast or gluten free oats are a great way to kick start the day with some fibre. Gluten free wholegrain and high fibre breads are a great source of fibre to include for lunch. For dinner add gluten free wholegrain pasta or rice to your meals and some beans or lentils. These tips should help you hit your 30g/day.
Fruit & vegetables: Fruits and vegetables are jam packed full of vitamins such as Vitamin C, minerals and antioxidants which all contribute to a healthy happy heart. Potassium found in bananas is great to help reduce blood pressure. Fruit and vegetables are naturally gluten free! Fruit and vegetables are handy snacks to chop up and eat raw, pairing your fruit with some yogurt or your vegetables with some hummus is a delicious way to meet your 5 a day. Adding fruit to your breakfast cereals or having a smoothie with lunch. Top smoothie tip is to add frozen fruits to create a delicious icy cold drink. With dinner making sure one third of your plate is nice a colourful with different vegetables will ensure youre getting a good variety in each day.
The guidelines for physical activity in Ireland are
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Why Would Tsh Be High
High TSH levels can mean your thyroid is not making enough thyroid hormones, a condition called hypothyroidism. Low TSH levels can mean your thyroid is making too much of the hormones, a condition called hyperthyroidism. Tests to diagnose Graves disease, an autoimmune disease that causes hyperthyroidism.
How can I control my thyroid at home? Add these to your diet: Foods that are rich in Vitamin A such as carrots and eggs. Seafood such as arame, dulce, kelp and nori that contain high levels of iodine. Foods that are rich in zinc such as beef, chicken, nuts and spinach. Increasing protein intake can help improve low thyroid function.
What Are The Best Foods To Heal The Thyroid
5 Foods That Improve Thyroid FunctionRoasted seaweed. Seaweed, such as kelp, nori, and wakame, are naturally rich in iodinea trace element needed for normal thyroid function. Salted nuts. Brazil nuts, macadamia nuts, and hazelnuts are excellent sources of selenium, which helps support healthy thyroid function. Baked fish. Frozen yogurt. Fresh eggs.Jan 12, 2018
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Liver Expression Of Lipoprotein Receptors And Other Metabolic Genes
At the conclusion of each study, liver was collected. Livers were homogenized in a RIPA buffer from Pierce Chemical Co. and protease inhibitors. Homogenates were used for Western blot analysis using the following antibodies against mouse proteins: anti-LDLR and anti-LDLR-related protein 1 , anti-SR-BI , and anti-glyceraldehyde 3-phosphate dehydrogenase .
Hepatic mRNA levels were assessed by real time PCR. Primers for each gene are included in Supplemental Table 1 published on The Endocrine Society’s Journals Online web site at .
Brazil Nuts May Lower Cholesterol
Another important reason for having a dose of one or 2 Brazil nuts every day is to reduce your cholesterol.
A small study on 10 volunteers found that consuming a number of Brazil nuts had a great impact on LDL cholesterol. This is the type of cholesterol that doctors say is bad cholesterol. Consuming Brazil nuts reduced bad cholesterol in a 6-hour period. At the same time, levels of HDL actually increased.
To help reduce your risk of stroke or heart disease, please read my article on how to lower cholesterol naturally.
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How Rapidly Can I Decrease My Ldl Cholesterol
Your levels of cholesterol could decrease as rapidly as just a few weeks to just a few months, relying in your remedy plan.
If your ranges are very excessive, your healthcare supplier could advocate taking medicines at the beginning of your remedy plan. This could assist decrease your levels of cholesterol extra rapidly. The sooner you possibly can decrease your bad levels of cholesterol, the earlier you possibly can decrease your danger for plaques to kind.
You can even decrease your ldl cholesterol via way of life and food regimen modifications alone, however it might take three to six months to see outcomes. Talk along with your healthcare supplier to determine one of the best remedy plan for you.
A Quick Review Of Thyroid Physiology And Lab Panels
The thyroid is a small butterfly-shaped gland that sits at the front of the neck. It receives a hormone signal from the pituitary and secretes other hormones into the bloodstream. You might be familiar with these hormones, which are included in a full thyroid panel:
Thyroid-stimulating hormone : This hormone is released by the pituitary gland and reflects the bodys need for thyroid hormone. This means that when TSH is high, not enough thyroid hormone is being produced . When TSH is low, there is more than enough thyroid hormone in the body .
Do you have heart disease or high cholesterol? You might want to get your thyroid checked
Thyroxine : The thyroid gland releases large amounts of this largely inactive form of thyroid hormone, which must be converted into the more active T3 by deiodinase enzymes. Low amounts of T4 may indicate hypothyroidism high amounts may indicate hyperthyroidism.
Triiodothyronine : This is the active form of thyroid hormone, secreted in small amounts by the thyroid gland and formed from the conversion of T4 to T3. T3 is the primary thyroid hormone that will act on cells all over the body to regulate metabolism. Low amounts of T3 may indicate hypothyroidism or low T3 syndrome high amounts indicate hyperthyroidism.
If thyroid medication is given for hypothyroidism, it is usually in the form of T4, T3, or a combination of the two.
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Find Your Balance The Marcelle Pick Approach
When we support our thyroid naturally, like with the thyroid diet, we can improve the way we feel on many levels. It may seem complicated, but once we learn which foods help and how to support our thyroid with the micronutrients we need, it will become second-nature. Here are some tips to help you get started.
Final Thoughts on the Thyroid Diet
Now that you have a little more information, you can take steps to support your thyroid with delicious meals. Isnt it great to know that the choices you make can have a huge positive impact on the way you feel?
Treating Hypothyroidism Reduces Atherosclerosis Risk
Am Fam Physician. 2004 Feb 1 69:656-657.
The relationship between hypothyroidism and atherosclerosis has been confirmed by case-control studies and autopsy the relationship is much clearer in patients with overt hypothyroidism than in patients with subclinical disease. Overt hypothyroidism increases low-density lipoprotein cholesterol levels, induces diastolic hypertension, alters coagulability, and negatively affects vascular smooth muscle function. Treatment of overt hypothyroidism can moderate these negative effects, but the effect of treatment is less clear in patients with subclinical hypothyroidism. Reductions in total cholesterol levels are highest in patients who had the highest pretreatment thyroid-stimulating hormone and lipid levels. Hypothyroidism treatment also can reduce hypertension and improve vascular smooth muscle function. Treatment of subclinical hypothyroidism may lower cholesterol levels in patients with hypercholesterolemia. Cappola and Ladenson reviewed the most recent information about hypothyroidism and cardiovascular risk factors.
Patients with hypothyroidism appear to have elevated homocysteine and C-reactive protein levels and altered flow-mediated, endothelium-dependent vasodilatation coagulation capacity also may be affected. Thyroxine therapy can reduce homocysteine and CRP levels significantly in persons with overt hypothyroidism, but it may not be as useful in patients with subclinical disease.
Read the full article.
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